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Search Results for " phosphatidylinositol 4 kinases "

13

Compounds

Cat No. Product Name Synonyms Targets
TQ0009 UCB9608 PI4K
UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.
T16530 BF738735 Antiviral , PI4K
BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM). BF738735 exhibits a broad spectrum of antiviral activity.
T27499 GSK-A1 HCV Protease , PI4K
GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepatitis C virus (HCV) potential.
T16125 MMV390048 Parasite , PI4K
MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. fal...
T16967 T-00127_HEV1 PI4K
T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta (IC50: 60 nM).
T12454 PI-273 Apoptosis , PI4K
PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
T12468 PI4KIIIbeta-IN-10 PI3K , PI4K
PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ (IC50 of 3.6 nM).
T2616 PIK-93 PIK 93 ATM/ATR , DNA-PK , Virus Protease , PI3K , Carbonic Anhydrase , PI4K , mTOR , HSV
PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
T5421 KDU691 Parasite , PI4K
KDU691 is a PI4K inhibitor.
T12469 PI4KIIIbeta-IN-9 PI3K , PI4K
PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ(IC50 of 7 nM). .
T4220 BQR-695 BQR695,NVP-BQR695 PI3K , Parasite , PI4K
BQR-695 (NVP-BQR695) is a phosphatidylinositol 4-kinase (PI4K) inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively.
T19840 GSK-F1 PI4KA inhibitor-F1 PI4K
GSK-F1 (PI4KA inhibitor-F1) is a novel potent PI4KA inhibitor.
T67845 ARUK2001607 PI3K
ARUK2001607 is a selective inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ, Kd= 7.1 nM). ARUK2001607 exhibits high selectivity over other >150 kinases.
TargetMol